Once you attempt the question then PrepInsta explanation will be displayed.
There are two alternating series here. The first one is the square of the multiples of {3², 6^{2}, 9^{2} and 12^{2}} and the second one is a series of alternating prime numbers (2, 3, 5, 7). The missing number is a part of the first series so the missing number is 92 = 81.